Neutrophil Mobilization into Peritoneal Fluid

Neutrophil mobilization into peritoneal fluid.

Adrenal steroids and neutrophil mobilization.

LTHOUGH it is true that adrenal glucocorticoids have found wide clinical application as effective anti-inflammatory agents, they must be used with caution since they can also cause an increased susceptibility to infection. The present investigation was prompted by a desire to gain additional information regarding the role of adrenal steroids in relation to the extravascular migration of polymor...

Penetration of sulbactam and ampicillin into peritoneal fluid.

Twenty-five patients undergoing elective intraabdominal surgery received either 1 or 2 g of ampicillin together with 1 g of sulbactam intravenously before surgery. The peritoneal levels of the agent were measured. Both compounds penetrated peritoneal fluid readily; the mean percentage of penetration by ampicillin was 92%; that of sulbactam was 96%. After 1 g of each agent, the peritoneal levels...

Turbid Peritoneal Fluid.

and pseudochylous ascites. Spontaneous bacterial peritonitis is suggested by a predominance of polymorphonuclear cells, a positive Gram stain or a positive culture.1 Chylous ascites refers to increased concentration of triglycerides (>200mg/dL)2 in the peritoneal fluid, typically the result of traumatic lymphatic obstruction, tumor, tuberculosis, filariasis, congenital abnormalities or nephroti...

Penetrability of Intravenous Biapenem Into the Peritoneal Fluid of Laparotomy Patients and the Peritoneal Pharmacodynamics Against Gram-negative Bacteria

This study examined the penetrability of biapenem into the peritoneal fluid (PF) of laparotomy patients and assessed the peritoneal pharmacodynamics against common gramnegative bacteria that cause intra-abdominal infections. Biapenem (300 mg) was administered by 0.5-h infusion to 10 patients before the laparotomy. The drug concentrations in both plasma and PF were determined, analyzed pharmacok...